Biotin, also known as vitamin H and coenzyme R, is a water-soluble vitamin and also belongs to the B vitamin group, B7. It is essential for the synthesis of vitamin C and is indispensable for the normal metabolism of fats and proteins. It is a necessary nutrient to maintain the human body's natural growth, development and normal human function and health.
Biotin is one of the B vitamins, also known as vitamin H, vitamin B7, Coenzyme R (Coenzyme R). In the 1930s, while studying yeasty feeding raw egg protein. Biotin is a member of the water-soluble B vitamin group. It is more abundant in liver, kidney, yeast and milk, and is an important factor for the fixation of carbon dioxide by organisms. It is easy to bind with a protein in egg white, and a large amount of raw protein can hinder the absorption of biotin leading to biotin deficiency, such as hair removal, weight loss, dermatitis and so on. Biotin plays an important role in biochemical pathways such as fat synthesis and glycogenesis.
Biotin is the lifesaver of bald people, not only to prevent hair and the top of the head to see the light quite effective, but also to prevent the common teenage white hair of modern people. It also plays an important role in maintaining skin health. As for the effect of calming the nervous system has not been proven, but it does help with depression and insomnia.
Biotin is a coenzyme of many carboxylases and acts as a CO2 carrier in carboxylase reactions.
Chinese name Vitamin H [3]
Vitamin H
D-Biotin [3]
Vitamin H (D-Biotin)
Biotin [3]
Vitamin B7 [3] unfolded
Biotin [3], Coenzyme R, D-biotin [3], D-(+) -biotin [3], VH
Class of water-soluble vitamins
Food source Strawberries
CAS58-85-5 [3]
EINECS200-399-3 [3]
Molecular formula C10H16N2O3S [3]
Molecular weight 244.3032
Melting point 232-233C
Specific rotation 89 º (c= 1,0.1 N NaOH)
Refractive index 90.5° (C= 2,0.1 mol/L NaOH)
catalogue
1. Character and stability
2 Performance and use
3 Features
4 Physiological function
5 Main Applications
▪ Health use
▪ Beauty use
▪ Research Use
6 Symptoms of deficiency
7 Toxicity
8 Food Sources
9 Tips
10 Knowledge Expansion
Character and stability
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EDITOR
It is a colorless long acicular crystal with a parallel ring of urea anombined with valeric acid side chain; Very slightly soluble in water (22mg/100ml water, 25ºC) and ethanol (80mg/100ml, 25ºC), more soluble in hot water and dilute lye, insoluble in other common organic solvents. It breaks down in the presence of strong alkalis or oxidants.
It can be stable for several days in medium strength acid and neutral solution, and poor stability in alkaline solution. It is fairly stable at ordinary temperatures, but high temperatures and oxidants can inactivate it.
Oral biotin is rapidly absorbed from the stomach and intestine, 80% of the biotin in the blood exists in free form and is distributed in all tissues of the body, with a large amount in the liver and kidney. After medication, most of the biotin is excreted from the urine in its original form, and only a small part is metabolized into biotin sulfur oxide and dinorbiotin [1]
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